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15th Juice Plus+ Study Just Published

July 8, 2009

The 15th clinical research study on Juice Plus+ has just been published in the International Journal of Food Sciences and Nutrition. The study was in a “healthy overweight population” with a mean Body Mass Index (BMI) of 27.1. The study done by the Georgetown University Medical Center showed that Juice Plus+ significantly improved blood serum levels of β-carotene and agr-tocopherol in the overweight population.

The researchers also found that participants with higher levels of fat in their body depleted their stores of these nutrients much faster after the wash-out period (after taking Juice Plus+ for 28 days, the participants stopped taking it for 28 days to measure how long the higher levels of nutrients would stay in the bloodstream).

Note the “carry over” effect. Even after the subjects stopped eating Juice Plus+, they had elevated beta-carotene and alpha-tocopherol levels for 2-4 weeks, depending on adiposity. This means that subjects with more body fat saw faster reductions in nutrient levels, whereas subjects with less body fat were able to hold on to those nutrients longer.

I don’t yet have access to the full study, but when I do I will update on the entire results of the study.

Here’s the study abstract for those medically minded:

Healthy overweight subjects (24 males, 68 females; mean age=48.8 years; body mass index=27.1±4.9) participated in a randomized, double-blind, placebo-controlled crossover study with two periods of 28-day supplementation using a nutritional product composed primarily of dehydrated juice concentrates from mixed fruits and vegetables (JuicePlus+®). Compared with placebo, supplementation for 28 days increased concentrations of serum β-carotene by 264% (P <0.001) and agr-tocopherol by 14% (P<0.01). After crossover of the active group to placebo, β-carotene and agr-tocopherol declined via first-order kinetics, with serum half-lives (t 1/2) for β-carotene and agr-tocopherol determined to be 22.8±3.1 and 4.6±2.3 days, respectively. Depletion rates for β-carotene correlated with adiposity (quartile 1, body mass index=21.96, t 1/2=17.6 days vs. quartile 4, body mass index=37.87, t 1/2=26.3 days; P<0.05). In conclusion, the supplementation period resulted in significantly elevated levels of β-carotene and agr-tocopherol, indicating bioavailability. These increased levels persisted 2-4 weeks after supplementation was discontinued, and the rates of depletion were correlated with the levels of general adiposity.

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